Fig. 5: Features/αHBs that contribute most to the αSA signal for different classifications.
From: Differential sensing with arrays of de novo designed peptide assemblies
a Feature importance of the 46 αHBs in the αSA in the differentiation of NASH and non-NASH sera samples. The top 5 features as determined by KBest analysis, ExtraTrees (ET) and permutation (perm) analysis are highlighted (red, blue and gold, respectively). The highest ranked αHB from each feature selection method is highlighted (*). The 10 αHBs that contribute most to signal in challenges with AAs (b), FAs (c), CHOs (d), and 2-way NASH sera classification (e). αHB rankings are taken from the combined rank of all three feature selection methods. Color scheme for b–e: Hydrophobic αHBs, yellow; polar mutations, green; charged mutations, blue; aromatic mutations, red.
