Fig. 4: Scope for the formation of Z isomer with aryl halides and isomerization/cross-coupling.
From: Modulating stereoselectivity in allylic C(sp3)-H bond arylations via nickel and photoredox catalysis
Unless otherwise specified, the reactions were performed on a 0.2 mmol scale under the following reaction conditions: alkene (3 equiv.), aryl halide (1 equiv.), 2,4,6-collidine (3 or 1.5 equiv.), PC-1 (1 mol%), NiBr2 (20 mol%), 6,6’-dmbpy (20 mol%), dioxane/THF 1:1 (2 mL), rt, 48-72 h, yields and Z/E after purification by chromatography (numbers in parentheses refer to Z/E before purification). + two parallel runs in 0.1 mmol were carried out with LiBr (1 equiv.) as additive.
