Fig. 7: PDAC dataset (CRA001160) analysis by scMGCA. | Nature Communications

Fig. 7: PDAC dataset (CRA001160) analysis by scMGCA.

From: Topological identification and interpretation for single-cell gene regulation elucidation across multiple platforms using scMGCA

Fig. 7

a Visualization of cell clusters identified by scMGCA via t-SNE (left) and the proportion of different cell types (right). b Visualization of the distribution of normal cells and cancer cells via t-SNE. c Heatmap of top 10 marker gene expression levels for each cell cluster, and the corresponding DNA binding motif for each cell cluster. d Visualization of expression distribution of the top marker gene of each cell cluster. e Violin plot of expression levels of top marker genes in each cell cluster. f Heatmap for pseudo-time analysis of marker genes. g GSEA on KEGG pathways for PDAC. h Hierarchical plot of communication between cell clusters in the Insulin signaling pathway. Source data are provided as a Source Data file.

Back to article page