Fig. 4: Structural comparison of the CD81-binding loop.
From: Regions of hepatitis C virus E2 required for membrane association
The superposition of a the bent CD81-binding loop of E2core+stem (red) with the retracted CD81-binding loop of eE2 (blue), b the extended CD81-binding loop of ΔHVR1 eE2 (green) and bent CD81-binding loop of E2core+stem (red), and c the extended CD81-binding loop of ΔHVR1 eE2 (green) and retracted CD81-binding loop of eE2 (blue). b, c tCD81-LEL bound to ΔHVR1 eE2 (green) is not shown. Adjacent backbone residues are gray. The location of Y529 and W531 side chains are shown as heteroatom sticks, and the distances are provided.
