Fig. 6: Safety and tolerability of CAB ISFI implants in rhesus macaques. | Nature Communications

Fig. 6: Safety and tolerability of CAB ISFI implants in rhesus macaques.

From: Ultra-long-acting in-situ forming implants with cabotegravir protect female macaques against rectal SHIV infection

Fig. 6

a Heatmap of local skin reactions at the implant site in the six ISFI-treated animals. Local skin reactions were scored using a Draize scale (0-none to 4-severe). b Histopathology of skin. One skin biopsy per animal was collected at the implantation from treated animals RH-1093, RH-1097, RH-42012 (n = 3) and an untreated control (n = 1). All scale bars represent 1 mm (H&E, original magnification ×4).

Back to article page