Fig. 2: Effectiveness of DIMES in matching the targets generated using experimental imaging data.
Comparison between the mean spatial distances computed from the reconstructed structures and the experimental data in cell lines: IMR90 (a), K562 (b), A549 (Supplementary Fig. 10a), and HCT116 (Supplementary Fig. 10b). The upper panel shows side-by-side comparisons of the distance matrices, and the lower panel displays the scatter plot between individual pairwise distances rij’s. The Pearson correlation coefficient is near unity (>0.99) for all of the cell types which shows the accuracy of the DIMES method. c–e Comparison between input distance map with missing data (lower triangle) and the full predicted distance map (upper triangle). A percentage of pairwise distances in the distance map are randomly chosen and set to be missing data (displayed in white). f rij for missing data versus the predicted values. The black line has a slope of unity.
