Fig. 2: The impact of routine pneumococcal vaccination in older adults aged ≥ 55 years old (y).
From: Optimal age targeting for pneumococcal vaccination in older adults; a modelling study
The expected absolute number of total IPD cases averted for the rest of age cohort lifetime by vaccinating every older adult in the age cohort stratified by country and vaccine product, under the scenario of age-independent initial vaccine efficacy/effectiveness (VE) and waning VE in Brazil, England, Malawi and South Africa. The red lines represent cohort model mean estimates and the shaded red ribbon represents 95% bootstrap confidence intervals for the mean estimates. The X corresponds to the optimal age for pneumococcal vaccination. In Brazil, Malawi and South Africa, most cases are preventable at age 55 years whereas in England this is achieved at age 70 years.
