Fig. 4: Manhattan plots showing the GWAS signals that colocalize with eQTLs. | Nature Communications

Fig. 4: Manhattan plots showing the GWAS signals that colocalize with eQTLs.

From: Fine mapping spatiotemporal mechanisms of genetic variants underlying cardiac traits and disease

Fig. 4

ae Manhattan plots showing the GWAS signals for five cardiac traits. Among all genome-wide significant SNPs, the GWAS signals that colocalize with eQTLs for eGenes are highlighted in purple, with eQTLs for eIsoforms (light brown), with eQTL signals for both eGenes and eIsoforms (green), and those that do not colocalize with eQTLs are shown in turquoise. Horizontal dashed blue line represents the genome-wide significance threshold (GWAS p = 5 × 10−8).

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