Fig. 7: Two distinct ParvOT neuronal populations promote analgesia via release of OT in the vlPAG and in the blood and spinal cord.
From: An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats

We hypothesize that two parallel parvOT pathways are activated by pathological, painful stimuli. Both pathways release OT in various brain regions and the periphery which then leads to a reduction in nociception.