Table 1 Estimate of genetic correlation among autoimmune-related diseases

From: Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

 

PSC

CD

UC

IBD

Lupus

PBC*

Primary sclerosing cholangitis (PSC)

1

0.24 (se = 0.07)

0.62 (0.08)

0.46 (0.06)

0.20 (0.10)

0.31 (0.09)

Crohn’s disease (CD)

 

1

0.62 (0.03)

0.92 (0.02)

0.13 (0.055)

0.18 (0.05)

Ulcerative colitis (UC)

  

1

0.90 (0.01)

0.22 (0.07)

0.23 (0.05)

Inflammatory bowel disease (IBD)

   

1

0.19 (0.05)

0.23 (0.04)

Lupus

    

1

0.49 (0.06)

Primary biliary cirrhosis (PBC)*

     

1

  1. The asterisk “*” indicates that imputed summary statistics were used to estimate the SNP-heritability and pairwise genetic correlation using the SSimp package. “se” stands for the standard error of the pairwise genetic correlation between PSC and each trait.
Back to article page