Fig. 3: Direct sequencing of rRNA polymorphism resolved by the high-resolution 70 S structure.
From: The translating bacterial ribosome at 1.55 Å resolution generated by cryo-EM imaging services
a Partial sequence alignment of H79 of the 23 S rRNA between the E. coli B-strain and MRE600. Base-swap positioning is indicated. Other observed mutations are indicated by an asterisk. b Snapshot of H79 shown as cartoon illustration with base colouring as in “a”. Overlaid cryo-EM density is shown as transparent isosurface. c Close-up of the base pair swap using B-strain sequence and MRE600 sequence (PDB 7K00) with overlaid EM density shown as mesh.
