Fig. 2: Details for carriers of the PKD2 p.Phe472*fs variant. | Nature Communications

Fig. 2: Details for carriers of the PKD2 p.Phe472*fs variant.

From: Imputation-powered whole-exome analysis identifies genes associated with kidney function and disease in the UK Biobank

Fig. 2

a Kidney ICD10 diagnosis by the carrier, color-coded (red—cystic kidney disease codes, blue—CKD codes). Carrier age was annotated in the columns. The median age was 60 (range 41–67). b Boxplot of eGFRcrea for the non-carriers of the p.Phe472*fs (4:88046737:TC:T) frameshift variant (left) and of the carriers (right); eGFRcrea of carriers ranged from 25 to 108 ml/min/1.73 m2 (mean 65, SD 28). The boxes represent the first to the third quartile, the horizontal line the median, and the whiskers extend to 1.5 times the interquartile range.

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