Fig. 3: Cryo-EM maps of prefusion NiV F in complex with neutralizing antibodies. | Nature Communications

Fig. 3: Cryo-EM maps of prefusion NiV F in complex with neutralizing antibodies.

From: Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

Fig. 3

Sharpened 3D reconstructions showing side views of Fabs in complex with NiV F prefusion trimer. NiV F protomers are shown as shades of orange/yellow/brown. A Fab 4H3 is colored pink, B Fab 2D3 is colored green, C Fab 1H8 is colored blue, D Fab 1A9 is colored purple, E Fab 1H1 is colored black and F Fab 2B12 is colored red. Heavy chains for Fabs are darkly shaded, light chains are lightly shaded. The stoichiometry of the NiV F complex with Fab 2D3 was 1:1 (Fab:NiV F trimer), while the other complexes were all 3:1 (Fab:NiV F trimer).

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