Fig. 7: ARID3A expression and rs2238574 genotypes are associated with disease severity. | Nature Communications

Fig. 7: ARID3A expression and rs2238574 genotypes are associated with disease severity.

From: A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression

Fig. 7

A Association of the numbers of hepatic ARID3A positive inflammation cells with hepatic inflammatory degrees (left) and fibrosis stages (right) in PBC patients. B Association of the numbers of hepatic ARID3A positive inflammation cells with serum ALT, AST, GGT, ALP, TBil, ALB, IgG and IgM levels. Association analysis are performed using Pearson’s correlation. C Association of rs2238574 genotypes with liver fibrosis (left) and inflammation (right) in subjects with PBC (C/C, n = 66; C/A, n = 113; A/A, n = 32). Correlation analysis are performed using logistic regression adjusted for disease history. ALT Alanine aminotransferase, AST aspartate transaminase, ALP alkaline phosphatase, GGT γ-Glutamyl transferase, TBil Total bilirubin, ALB albumin, IgG immunoglobulin G, IgM immunoglobulin M.

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