Table 1 Phylogenetic and epidemiological features of Escherichia albertii Bayesian Analysis of Population Structure (BAPs) clusters for isolates from Great Britain
From: The genomic epidemiology of Escherichia albertii infecting humans and birds in Great Britain
Genomic features | Isolate composition | Statistical support and nomenclature | ||||||
---|---|---|---|---|---|---|---|---|
BAPS cluster | Congruence with phylogeny | Average pairwise distance | Total isolates (n) | Human (% of cluster) | Wild bird (% of cluster) | Captive bird (% of cluster) | Proportion humans [Proportion (95% confidence interval), two-tailed p-value] | Final determinationa |
1 | Monophyletic | 79 | 4 | 4 (100) | 0 (0) | 0 (0) | 1.00 (0.40–1.00), p = 0.1232 | HAC |
2 | Monophyletic | 28 | 17 | 17 (100) | 0 (0) | 0 (0) | 1.00 (0.80–1.00), p < 0.0001 | HAC |
3 | Monophyletic | 132 | 7 | 7 (100) | 0 (0) | 0 (0) | 1.00 (0.59–1.00), p = 0.0156 | HAC |
4 | Monophyletic | 25 | 16 | 16 (100) | 0 (0) | 0 (0) | 1.00 (0.79–1.00), p < 0.0001 | HAC |
5 | Monophyletic | 167 | 4 | 4 (100) | 0 (0) | 0 (0) | 1.00 (0.40–1.00), p = 0.1232 | HAC |
6 | Monophyletic | 967 | 61 | 12 (20) | 49 (80) | 0 (0) | 0.20 (0.11–0.33), p < 0.0001 | BAC |
7 | Monophyletic | 73 | 29 | 4 (14) | 24 (86) | 1 (3) | 0.17 (0.05–0.35), p = 0.0003 | BAC |
8 | Polyphyletic | 3169 | 24 | 19 (79) | 1 (4) | 4 (17) | 0.80 (0.58–0.93), p = 0.0148 | HAC |
Total | NA | NA | 162 | 85 | 74 | 5 |