Table 2 Antimicrobial resistance phenotypes of 11 Escherichia albertii isolates with varied antimicrobial resistance genotypes

From: The genomic epidemiology of Escherichia albertii infecting humans and birds in Great Britain

Sequence Read Archive Accession

Genotypea

Minimum inhibitory concentration (μg/mL)c

Cephalosporin

Fosfomycin

Tetracycline

β-lactam

Fluoroquinolone

Chloramphenicol

Rifampicin

Cefoxitin

Ceftriaxone

Fosfomycin

Tetracycline

Ampicillin

Ciprofloxacin

Chloramphenicol

Rifampicin

SRR12769799

uhpT_E350Q*, marR_S3N*, parE_I355T*

8

0.047

1

1.5

3

0.016

6

8

SRR12769953

uhpT_E350Q*, marR_S3N*, parE_I355T*

6

0.047

6

0.5

4

0.008

3

2

SRR13049225

uhpT_E350Q*, marR_S3N*, parE_I355T*

6

0.047

2

1

4

0.006

4

4

SRR13049237

uhpT_E350Q*, parE_I355T*

6

0.047

1

1

4

0.012

6

3

SRR11442290

uhpT_E350Q*, marR_S3N*, parE_I355T*, gyrA_S83L*

4

0.047

1.5

0.75

6

0.125

3

12

SRR15338008

uhpT_E350Q*, marR_S3N*, gyrA_S83L*, parE_I355T*

1.5

<0.016

1.5

0.38

3

0.032

2

4

SRR8981835

uhpT_E350Q*, marR_S3N*, gyrA_S83L*, parE_I355T*

1.5

<0.016

1.5

0.25

3

0.032

2

4

SRR15338057

blaDHA-1, uhpA_G97D*, uhpT_E350Q*, tet(A), marR_S3N*, blaTEM-1, gyrA_S83L*, parE_I355T*, qnrB4

6

0.064

12

48

>256

0.38

1.5

4

SRR9050433

blaDHA-1, uhpA_G97D*, uhpT_E350Q*, tet(A), marR_S3N*, blaTEM-1, gyrA_S83L*, parE_I355T*, qnrB4

1

0.047

8

48

96

0.5

3

16

SRR11425059

uhpT_E350Q*, tet(A), marR_S3N*, blaTEM-1, gyrA_S83L*, parE_I355T*

12

0.064

2

48

>256

0.19

4

8

SRR3574322

uhpT_E350Q*, tet(A), marR_S3N*, blaTEM-1, gyrA_S83L*, parE_I355T*

3

<0.016

1

32

96

0.023

4

4

Genotype associated with resistanceb

blaDHA-1

uhpA_G97D*, uhpT_E350Q*

tet(A), tet(B), marR_S3N*

blaTEM-1, blaTEM-135, marR_S3N*

gyrA_S83L*, parC_S57T*, parE_I355T*, qnrB19, qnrB4, qnrS13, marR_S3N*

marR_S3N*

marR_S3N*

  1. aGenes and point mutations (*) found present in isolates in this study.
  2. bGenes and point mutations (*) associated with resistance to antimicrobial classes tested in this study.
  3. cUnderlined MIC determination results highlight MIC breakpoints (⌠g mL−1) classed as resistant according to EUCAST guidelines. (https://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Breakpoint_tables/v_11.0_Breakpoint_Table).