Table 1 Clinical characteristics of TNBC patients

From: Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers

  

n (%)

Mean age at diagnosis (range)

 

54 (29–88)

TNM

T0

0 (0)

T1

15 (29.1)

T2

31 (54.5)

T3

9 (16.4)

T4

0 (0)

N0

36 (65.4)

N1

10 (18.2)

N2

7 (12.7)

N3

2 (3.6)

M0

51 (92.7)

M1

4 (7.3)

Breast surgery (n = 55)

Tumorectomy

32 (58.1)

Mastectomy

23 (41.8)

Nodes surgery (n = 50)

Sentinel node biopsy

9 (18)

Lymphadenectomy

41 (82)

Histologic type

No special type

49 (89.1)

Metaplastic

6 (10.9)

SBR grade (n = 43)

Grade SBR 1

0 (0)

Grade SBR 2

2 (4.7)

Grade SBR 3

41 (95.3)

Type of chemotherapy (n = 46)

Anthracycline then taxane

30 (55.6)

Anthracycline based

10 (18.5)

Taxane based

4 (7.4)

Others

2 (3.7)

No

8 (14.8)

Radiotherapy

Yes

48 (87.3)

No

7 (12.7)

Relapse

No

25 (45.5)

Local only

1 (1.8)

Distant metastasis

29 (52.7)

  1. TNM: classification of malignant tumours (tumour, lymph node, metastasis). SBR grade: Scarff Bloom and Richardson.