Fig. 5: ICG alleviates AMA toxicity in mice liver organoids. | Nature Communications

Fig. 5: ICG alleviates AMA toxicity in mice liver organoids.

From: Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity

Fig. 5

The Organoids were treated with AMA (3 μM) and/or ICG (10 μM) for 3 days. a Representative images of mouse liver organoids. b Maximum diameter of organoids (n = 8 randomly selected organoids in each figure). ***p = 0.0002, *p = 0.0248. The statistics were assessed using one-way ANOVA followed by Tukey’s multiple comparisons test. c Calcein/PI viability assay of organoids. d Representative H&E images of organoids. Data are presented as mean ± SD.  and are representative of three independent experiments. Source data are provided as a Source Data file.

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