Table 1 Abnormal bone mineral density values in WS patients

	Gender	Chronic treatment	Lumbar spine	Femoral neck
P1	Female	No	−3.1^a	0
P2	Female	No	−1.1	−1.8
P3^b	Male	Yes^c	−1.8	−2.3
P4	Female	Yes^d	−2.7	−1.3
P5^b	Male	Yes^e	−1.8	−2.2

Characteristics of each patient with low BMD value are shown. Four patients carry the CXCR4^R334X mutation and one displays the CXCR4^S338X mutation. There were 3 women and 2 men with an average age of 33.2 years (range 13–52). T-scores for lumbar spine (L1-L4) and femoral neck have been evaluated. According to World Health Organization (WHO) criteria, values classify patients as osteopenic with a T-score between −1.0 and −2.5 or osteoporotic with a T-score at or below −2.5.
^aValues outside the normal range defined by WHO are italicized.
^bFor patients 3 and 5, because of their young age, Z-scores are given with a value at or below −2.0 considered as abnormal.
^cG-CSF since age of 2.
^dG-CSF several years at the time of scan.
^eG-CSF for 6 months at the time of scan.

Quick links

Search