Fig. 3: Papillary fibroblasts interacted with cutaneous nerves in the inflamed skin.
From: Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis
a Representative whole-mount images of non-lesional or lesional skin stained for βIII tubulin (green) of IMQ-induced self-control PdgfraDreER-tdTomato mice (n = 3). Scale bar, 50 μm. b Tracing strategy of TncDreER-tdTomato mice. c Schematic diagram of IMQ-induced psoriasis mouse model in self-control TncDreER-tdTomato mice. d Representative whole-mount images of non-lesional or lesional skin of self-control TncDreER-tdTomato mice in (c, n = 3). Scale bar, 15 μm. e Representative whole-mount images of lesional skin stained for βIII tubulin (yellow), and CD3e (green) of TncDreER-tdTomato mouse lesional skin in (c n = 3). Scale bar, 50 μm. Data are representatives of two or three independent experiments.
