Fig. 2: Kaplan–Meier analysis of recurrence as a function of HLA-DR or IDO1 abundance in All Intraepithelial and All Stromal segments. | Nature Communications

Fig. 2: Kaplan–Meier analysis of recurrence as a function of HLA-DR or IDO1 abundance in All Intraepithelial and All Stromal segments.

From: Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer

Fig. 2

Tumor-average protein counts were used to stratify samples into tertiles (high = black, mid = blue, low = orange) based on the abundance of HLA-DR or IDO1. Kaplan–Meier analysis was carried out using protein abundance and time to event as continuous variables. Log-rank p-values are given, with the number of patients “at risk” shown below each curve. Source data are given in Supplementary Data 2. KM analysis of recurrence as a function of PD-L1 or IDO1 in CD45EnR Intraepithelial, CD68EnR Intraepithelial, TumorEnR Intraepithelial, CD45EnR Stroma, and CD68EnR Stoma segment classes are shown in Supplementary Figs. 6 (HLA-DR) and 7 (IDO1). HLA-DR abundance is given in All Segments (a), Intraepithelial segments (b), and Stromal segments (c); whereas IDO1 abundance is given in All Segments (d), Intraepithelial segments (e), and Stromal segments (f).

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