Fig. 7: Tolerability of CCD/RBD-HR in mice. | Nature Communications

Fig. 7: Tolerability of CCD/RBD-HR in mice.

From: Cationic crosslinked carbon dots-adjuvanted intranasal vaccine induces protective immunity against Omicron-included SARS-CoV-2 variants

Fig. 7

BALB/c mice (n = 5 per group) were intranasally immunized with 100 μg CCD and 10 μg RBD-HR on days 0, 14, and 28. On day 35, blood samples were collected for the assessment of complete blood count parameters (a) and biochemical indexes (b). The middle line is representative of the median, the whiskers are indicators of the value range, and the box shows the interquartile range. c Hematoxylin and eosin staining of the vital organs and nasal mucosa. Scale bar, 100 μm. Source data are provided as a Source Data file.

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