Fig. 2: PRC2 mutations are unique to MPNST-G1. | Nature Communications

Fig. 2: PRC2 mutations are unique to MPNST-G1.

From: Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities

Fig. 2

a Nonsynonymous mutations per megabase for benign neurofibromas, atypical neurofibromas and MPNSTs (n = 55 samples) compared to other childhood neuronal cancers and sarcomas from several cancer sequencing projects. Boxplots show the median, first and third quartiles (boxes), and the whiskers encompass the 1.5X the interquartile range. b Results from whole exome sequencing (n = 54) with frequency and mutations identified. c Schematic of the distribution of the mutations along the PTPRD gene.

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