Fig. 4: Single-copy coral orthologs with significant differences in expression between disease states. | Nature Communications

Fig. 4: Single-copy coral orthologs with significant differences in expression between disease states.

From: Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae

Fig. 4

The 31 annotated single-copy orthologs identified by EVE as highly variable (exhibiting expression plasticity across species and samples) that show the most significant differential expression between disease states (TukeyHSD; p ≤ 0.01). a Heatmap plots the relative expression of those 31 highly variable orthologs averaged across disease state: C Control (n = 25), E Exposed (no lesion, n = 8), and I Infected (with lesion, n = 19). b Boxplots show the rlog transformed expression of relevant orthologs in each sample, organized by coral species on the left and by disease status on the right. Color of gene headers correspond to biological function obtained from literature searches and Uniprot. Color of boxplots correspond to experimental disease status. P-values represent TukeyHSD results following one-sided ANOVA tests (*) = p ≤ 0.05; (**) = p ≤ 0.01, (***) = p ≤ 0.001. Boxplot elements: center line, median; box limits, upper and lower quartiles; whiskers, 1.5x interquartile range; points beyond whiskers, outliers).

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