Fig. 6: Single-copy symbiont orthologs with significant differences in expression between disease states. | Nature Communications

Fig. 6: Single-copy symbiont orthologs with significant differences in expression between disease states.

From: Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae

Fig. 6

The 24 annotated single-copy orthologs identified by EVE as highly variable (exhibiting expression plasticity across genera and samples) that show significant differential expression between disease states (TukeyHSD; p ≤ 0.05). a Heatmap plots the relative expression of those 26 highly variable orthologs averaged across disease state: C Control (n = 24), E Exposed (no lesion, n = 8), and I Infected (with lesion, n = 19). b Boxplots show the rlog transformed expression of relevant orthologs in each sample, organized by dominant symbiont genera on the left and by disease status on the right. Color of gene headers correspond to biological function obtained from literature searches and Uniprot. P-values represent TukeyHSD results following one-sided ANOVA tests (*) = p ≤ 0.05; (**) = p ≤ 0.01, (***) = p ≤ 0.001. (A = Symbiodinium, B = Breviolum, C = Cladocopium, D = Durusdinium). Boxplot elements: center line, median; box limits, upper and lower quartiles; whiskers, 1.5x interquartile range; points beyond whiskers, outliers).

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