Table 1 Summary of the best model of the Hierarchical Linear Regression analysis using GABA to predict Glu levels while controlling for Group and Voxels: Glu~GABA*Group + Voxel

From: Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls

Coefficients

β-estimates

Std.Error

t-test

p-value

Intercept

10.48

0.46

22.63

<2e−16

GABA

1.82

0.45

4.00

9.23e−05

Group (OCD)

1.33

0.58

2.30

0.02

Voxel (OCC)

−2.09

0.16

−13.06

<2e−16

Voxel (SMA)

0.01

0.16

0.07

0.98

GABA:Group(OCD)

−1.05

0.58

−1.81

0.07

  1. The data for this table are provided in the Source Data file and the code is provided in the Supplementary Information. For the ACC voxel, the sample size for Glu and GABA in the OCD group was (n = 30) and in HV (n = 30). For the SMA voxel, the sample size for Glu in the OCD group was (n = 31) and in the HV it was (n = 30), for GABA in the OCD group it was (n = 30) and in the HV the sample size was (n = 29). Lastly, for the OCC voxel, the sample size for Glu in the OCD group was (n = 30) and in the HV it was (n = 28), for GABA in the OCD group it was (n = 27) and in the HV the sample size was (n = 29).
  2. GABA γ-amino-butyric acid, Glu glutamate, SMA supplementary motor area, OCC occipital cortex, OCD obsessive-compulsive disorder.
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