Table 3 Clinical and demographic information for healthy volunteers and participants with OCD

From: Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls

 

OCD (M ± SD)

HV (M ± SD)

t-test

DF

p

d

95% CI

N

31

30

     

Age (years)

30.79 ± 9.99

32.16 ± 12.98

−0.46

59

0.64

−0.12

[−7.29, 4.55]

Gender (% female)

55%

50%

0.143 \({\,\!}^{{{{\mathrm{X}}}}^{2}}\)

1

0.70

−0.05 Phi

[0.30, 2.25]

Education (years)

15.35 ± 2.85

17.23 ± 2.72

−2.62

59

0.01

−0.67

[−3.31, −0.44]

Verbal IQ

110.21 ± 6.13

113.11 ± 7.75

−1.62

59

0.11

−0.41

[−6.48, 0.67]

MADRS

17.65 ± 11.01

5.07 ± 3.78

6.00

37.20

<0.001

1.52

[8.33, 16.82]

STAI-S

37.65 ± 9.12

27.70 ± 6.83

4.80

59

<0.001

1.23

[5.80, 14.08]

STAI-T

56.55 ± 11.03

37.13 ± 10.80

6.94

59

<0.001

1.77

[13.81, 25.01]

YBOCS total

22.94 ± 5.90

NA

NA

NA

NA

NA

NA

YBOCS obsessions

11.45 ± 3.21

NA

NA

NA

NA

NA

NA

YBOCS compulsions

11.52 ± 2.97

NA

NA

NA

NA

NA

NA

OCI total

63.32 ± 30.37

6.07 ± 5.80

924U

NA

<0.001

−0.73\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[45.0, 66.0]

OCI washing

10.48 ± 9.86

1.00 ± 1.39

793U

NA

<0.001

−0.38\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[2.0, 11.0]

OCI checking

13.06 ± 8.28

1.23 ± 1.45

868U

NA

<0.001

−0.58\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[9.0, 14.0]

OCI doubting

6.26 ± 3.56

0.23 ± 0.62

874U

NA

<0.001

−0.63\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[4.0, 9.0]

OCI ordering

7.29 ± 5.24

1.30 ± 1.49

836U

NA

<0.001

−0.48\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[3.0, 7.0]

OCI obsessions

14.42 ± 8.11

0.73 ± 1.20

896U

NA

<0.001

−0.66\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[11.0, 16.0]

OCI hoarding

3.16 ± 2.86

0.93 ± 1.72

696U

NA

<0.001

−0.19\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[1.0, 3.0]

OCI neutralisation

8.65 ± 5.77

0.73 ± 0.94

878U

NA

<0.001

−0.60\({\,\!}^{{\upeta_{\rm p}}{\,\!}^2}\)

[4.0, 10.0]

IUS

84.61 ± 22.85

54.37 ± 16.93

5.88

59

<0.001

1.50

[19.91, 40.58]

HTQ compulsivity

23.87 ± 4.21

13.60 ± 5.56

8.15

59

<0.001

2.08

[7.75, 12.81]

  1. The sample size for OCI in healthy group is 28 because two participants did not provide these data, for the rest of the data there were 30 healthy subjects and 31 participants with OCD. The tests used for age, gender, education and verbal IQ were two-sided, and the rest of the variables were tested using a one-sided test. The data for this table are provided in the Source Data file.
  2. NA Not Applicable, CI Confidence Interval, MADRS Montgomery- Asberg Depression Rating Scale, STAI-T State Trait Anxiety Inventory- Trait, STAI-S State Trait Anxiety Inventory- State, YBOCS Yale Brown Obsessive Compulsive Scale, OCI Obsessive-Compulsive Inventory, IUS Intolerance of Uncertainty Scale, HTQ Habitual Tendencies Questionnaire, HV healthy volunteers, OCD obsessive compulsive disorder, DF degree of freedom, U Mann–Whitney U test for not normally distributed data, X2 Chi-Square test for categorical data, ηp2 partial eta-square (a measure of effect size for the U test), Phi a measure of effect size for the X2 test, d Cohen’s d, CI Confidence Interval of the t-test.
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