Fig. 1: Strategies for intermolecular enantioselective construction of alkyl-alkyl bonds.

a Enantioselective C_sp3-C_sp3 bond-forming from alkyl-M and alkyl electrophiles. b Enantioselective C_sp3-C_sp3 bond-forming from alkenes and alkyl electrophiles. c Enantioselective C_sp3-C_sp3 bond-forming from two alkyl electrophiles.