Fig. 3: Anomalous diffusive behavior of sporozoites.
From: Plasmodium sporozoite search strategy to locate hotspots of blood vessel invasion
a Hurst exponent of blood vessel invaders (INV, blue circles) and non-invaders (NINV, red circles). Symbols represent the average of sporozoites (27 for INV and 161 for NINV) from seven independent experiments ±95% confidence interval. H > 0.5, superdiffusion. H < 0.5, subdiffusion. b k-means clustering of the slope (m) of MSD plotted in log-log scale against the analysis time window for the NINV population. Top graph represents the parasite percentage in each cluster (c1: brown, c2: red, c3: orange). c Hurst exponent time series for sporozoites from clusters c1 (brown), c2 (red) and c3 (orange). Symbols represent the average, and lines represent individual parasites. d Representative examples as shown in (c) of a superdiffusive, forward-moving parasite (c1, brown), a subdiffusive, meandering, circularly moving parasite (c3, orange), and an intermediate behavior between the two previous phenotypes (c2, red). Bar = 50 µm. Source data are provided as a Source Data file.
