Fig. 5: Protective efficacy of the HLJ/18-7GD vaccine against challenge with different ASFVs in pigs. | Nature Communications

Fig. 5: Protective efficacy of the HLJ/18-7GD vaccine against challenge with different ASFVs in pigs.

From: Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

Fig. 5

Groups of five SPF pigs were vaccinated with 106 TCID50 of HLJ/18-7GD, and then intramuscularly challenged with 103 HAD50 of HLJ/18 (a–c) or the recombinant virus JS/LG/21 (d–f) on day 28 post-vaccination. Groups of four unvaccinated SPF pigs were challenged as controls. The rectal temperature (a, d) and survival (b, e) were monitored daily, and tissue samples (c, f) were collected from dead pigs or euthanized pigs at the end of the observation period for viral DNA detection using qPCR. The dashed black lines indicate the normal rectal temperature (40 °C) of pigs. LN1, inguinal lymph node; LN2, submaxillary lymph node; LN3, mediastinal lymph node. Source data are provided as a Source Data file.

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