Table 1 Distribution of antimicrobial resistance (AMR) genes across the chromosome and different types of plasmids found in representative super-lineage A S. Concord genomes

From: A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia

Lineage

Lab ID

Location

Size (bp)

AMR genes

Insertion sequences or transposons in AMR cassettes

3

95907

Chromosome

14495

sul2, aph(3”)-Ib, aph(6)-Id

IS26, IS5075, ISStma11

IncHI2 plasmid

288445

catA2, dfrA19, sul1, sul2, blaCTX-M-15, blaSHV-12, qnrA1

IS1353, IS26, Tn2, ISEc63, IS1247, IS6100, ISPa38, IS5075, IS903

3

64206

Chromosome

13168

sul2, aph(3”)-Ib, aph(6)-Id

IS26, ISStma11

IncHI2 plasmid

372354

catA2, dfrA19, sul1, sul2, blaCTX-M-15

IS26, Tn2, ISEc63, IS1247, IS6100, ISPa38, IS5075

4

1035531

Chromosome

91371

blaSCO-1, blaOXA-10, dfrA23, catA2, cmlA5, sul1, sul2, blaCTX-M-15

IS1353, IS26, IS4321R, ISCfr1, ISPa40, ISPmi2, ISStma11, TnAs1

IncI1α plasmid

85904

blaTEM-1

Tn3, Tn2

4

254833

Chromosome

55792

blaOXA-10, dfrA23, catA2, cmlA5, sul1, sul2

IS1353, IS26, IS4321R, ISCfr1, ISPa40, ISStma11, TnAs2

IncA/C2 plasmid

71024

dfrA7, sul1, blaCTX-M-15

IS26, ISEcp1

IncI1α plasmid

85904

blaTEM-1

Tn3, Tn2

5

0508H45184

IncHI2/IncA/C2 hybrid plasmid

415479

dfrA12, sul1, sul2, floR, blaTEM-1, catA2, blaCTX-M-15, mph(A)

Tn2, ISEc63, IS26, ISEcp1, IS103, ISKpn8, ISEsa1, ISEsa2, IS1D, IS1R, ISBcen27, ISKpn21, IS903, ISVvu2, Tn3

5

70366

Chromosomally integrated IncHI2 plasmid

270994

dfrA19, sul2, catA2, blaTEM-1, blaSHV-12, qnrB2

IS103, IS26, IS4321R, IS903, ISBcen27, ISEc63, ISEsa1, ISEsa2, ISKpn21, ISKpn8, Tn2

IncA/C2 plasmid

160357

floR, blaTEM-1, sul1, sul2, mph(A), blaCTX-M-15

IS26, IS1247, IS6100, ISEcp1, Tn2

8

850890

IncHI2 plasmid

294257

blaTEM-1, dfrA14, sul2, catA1, blaOXA-1, blaCTX-M-15, qnrB1, aac(6’)-Ib-cr5

IS26, IS1×2, IS6100, IS3000, ISKpn11, Tn2, ISPa38, IS5075, ISEcp1, IS1R, IS1D

  1. Reference genomes were constructed from Oxford Nanopore reads and polished with Illumina reads. The size column reports the size in base pairs (bp) of each chromosomal integration or plasmid. Only AMR genes that were exact database matches and contributed to the MDR, XDR or PDR genotype were listed. Reference genomes for three susceptible isolates (with laboratory identifiers 679052, H044240362 and H04340470) were not shown.