Fig. 2: Asymmetric hydrogenation of ketones using Ir/phamidol catalyst.
From: A 13-million turnover-number anionic Ir-catalyst for a selective industrial route to chiral nicotine

A Laboratory scale asymmetric hydrogenation of representative benchmark acetophenone and nitrogen-containing aromatic ketones. B Laboratory scale-up asymmetric hydrogenation of nitrogen-containing ketone as a key step in a novel selective route to chiral nicotine.