Fig. 6: Conjugation of C(7) maleimidated tryptophan/peptide with biomolecule containing sulfhydryl groups.
From: Modular synthesis of clickable peptides via late-stage maleimidation on C(7)-H tryptophan
Reaction conditions: 3, 5, 7 or 9 (0.04 mmol), 11 (0.08 mmol), Et3N (10 µL), DCM (1 mL), room temperature, 3–6 min.
