Fig. 1: AFM imaging experiments reveal the effect of AMC-109 addition to S. aureus lipid membranes.
From: Lateral membrane organization as target of an antimicrobial peptidomimetic compound
a AMC-109 chemical structure. b S. aureus lipid membranes upon treatment with AMC-109. Membranes are visualized untreated (left) and treated by subsequent additions of 1 µg/ml AMC-109 (0, 1, 2, 3, 4 μg/ml). Changes in the background colour originate from a combination of the membrane thinning and coverage of the mica by AMC-109. Representative of 3 independent experiments. c Area of the mica surface covered by the membrane upon subsequent additions of 1 µg/ml AMC-109. For each concentration, coverage of 10–12 areas in a 3×3 µm image size were evaluated. 3×3 µm images for area evaluation were gathered across 3 independent experiments (3–4 images for each AMC-109 concentration per experiment). Error bars represent standard error of the mean. Individual data points are depicted in grey. Source data for panel c are provided as a Source Data file.
