Fig. 9: Schematic summary of cytosolic Ptbp2 functions in axon growth.

a Ptbp2 binds to the 3′ UTR of Hnrnpr mRNA in motoneurons. b Ptbp2 regulates hnRNP R translation in association with eIF5A2. Ptbp2 controls axonal localization (c) and translation (d) of Hnrnpr mRNA in motoneurons. e Ptbp2 modulates axon growth of motoneurons.