Fig. 4: Reproducibility analysis results and association between subject-level and group-level differences. | Nature Communications

Fig. 4: Reproducibility analysis results and association between subject-level and group-level differences.

From: Parsing altered gray matter morphology of depression using a framework integrating the normative model and non-negative matrix factorization

Fig. 4

A Distribution of the correlation coefficients between the four disease factors identified using the overall patients and that using a patient subset (90%) (N = 100). B Factor composition of all patients is embedded into 4 into two-dimensional space. The orange hexagram represents subject-level differences of each patient, and the red circle represents group-level differences (“average” patient). C The correlations between the predicted weights and the true weights in the validation dataset 1. Shadow represent the empirical 95% confidence interval. PW1 weight of positive factor 1, PW2 weight of positive factor 2, NW1 weight of negative factor 1, NW2 weight of negative factor 2. Source data are provided as a Source Data file.

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