Table 1 Clinicodemographic characteristics

From: Parsing altered gray matter morphology of depression using a framework integrating the normative model and non-negative matrix factorization

 

Discovery dataset

Validation dataset 1

Validation dataset 2

 

Depression

(N = 105)

HCs

(N = 130)

p

Depression

(N = 76)

HCs

(N = 68)

p

HCs

Male, No. (%)

50.48%

45.38%

0.963a

39.47%

51.47%

0.843a

38.01%

Age, mean (SD), [range], y

20.30 (5.04) [11–37]

21.05 (5.33) [12–36]

0.256b

24.76 (6.58) [14–37]

25.06 (5.12) [18–37]

0.766b

45.10 (17.30)

[19–80]

Educational level, mean (SD), y

12.81 (5.13)

13.56 (4.49)

0.230b

13.51 (2.76)

16.38 (2.19)

2.106e−10 b

HAMD, mean (SD)

22.26 (6.19)

27.60 (7.87)

Age of onset, mean (SD), y

18.83 (4.94)

28.69 (11.55)

Anxiety/somatization, mean (SD)

5.77 (2.56)

Weight, mean (SD)

0.15 (0.51)

Cognitive impairment, mean (SD)

2.92 (2.46)

Psychomotor slowing, mean (SD)

8.55 (2.00)

Sleep disturbance, mean (SD)

4.21 (2.25)

IQR, mean (SD)

1.98 (0.14)

2.09 (0.29)

<0.001b

1.99 (0.10)

1.98 (0.11)

0.759b

 
  1. HC healthy control, HAMD Hamilton rating scale for depression, a χ2 test, b two-sided two-sample t test, IQR Image Quality Rating.
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