Table 1 Success rate of different genome mining approaches across 84 RiPPs

From: HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search

Median (Exact Matches)

 

ORF

Core

RiPP

seq2ripp

1.0 (61)

0.970 (40)

0.932 (12)

antiSMASH

0.353 (4)

  

BAGEL4

0.975 (42)

  

NeuRiPP

0.487 (30)

  

NLPPrecursor

 

0.934 (26)

 

RiPPMiner

 

0.375 (28)

0.867 (6)

  1. Reported are the median metric and the number of exact matches of each method for each pipeline step it supported. ORF and core detection metrics are maximum normalized Levenshtein similarity to the correct core. The RiPP metric is the maximum Tanimoto similarity between true and predicted structures. The distributions of scores are shown in Figure S14.
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