Fig. 2: Scope of the acceptors.
From: Organophotocatalysed synthesis of 2-piperidinones in one step via [1 + 2 + 3] strategy
The reaction was conducted using 1 (0.1 mmol), 2 (0.2 mmol) under standard conditions unless otherwise noted. Diastereomeric ratio (dr) was determined by 1H NMR of crude mixture of the reaction. Isolated yield after flash chromatography. The disordered part, solvent molecules and hydrogen atoms of crystal structures have been omitted for clarity, for details, see Supplementary Figs. 15 and 16. aCorresponding Weinreb amide was used. b5 mol% photocatalyst was used.
