Fig. 2: Evaluation of establishment of hookworm infections.
From: Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes
A Peripheral blood eosinophil counts (median ± IQR) at each evaluation visit, shaded area indicates normal range (Sample size for month 0, 6, 12, 18 and 24: Placebo n = 12, 12, 9, 8 and 6; L3-20 n = 13, 12, 11, 11 and 8; L3-40 n = 11, 11, 10, 8 and 8, respectively). # Indicates significantly different to 0 months; Tukey’s posthoc test: (B) Heat map displaying eosinophil counts the 6 month visit (peak eosinophilia) in each participant and correlation with the (C) detection of hookworm eggs in faeces by qPCR (Hookworm patency). Some samples were unable for analysis due to dropping out prior to the 6-month visit. D Quantification of hookworm eggs per gram (EPG) in faecal samples at 6 months (median, and individual data points, L3-20 n = 12, L3-40 n = 9). Source data are provided as a Source Data File.
