Fig. 2: Localization of the N-terminal domains A and B in RyR2.

a 3D visualization of the human RyR2 cryo-EM model (PDB ID: 7UA5) is shown in grey. Domains A and B are shown in blue and red, respectively. Cysteine residues are shown in green. b Localization of the truncation site in the AB-truncated hRyR2 mutant (hRyR2^ΔAB) on the primary structure.