Table 1 Features of eight differentially methylated CpG positions among breast cancer and normal controls group

From: A multiplex blood-based assay targeting DNA methylation in PBMCs enables early detection of breast cancer

Probe ID

Δβ value (BC-NC) *

P Value

Adjust P Value

CHR

UCSC_RefGene

UCSC_RefGene_Group

cg14507403

−0.151771106

4.92E-05

0.047018976

7

LMTK2

Body

cg09821790

−0.09869485

5.12E-05

0.047837259

16

SLC7A6

Body

cg15694422

−0.094113112

2.92E-07

0.01187436

3

MGLL

Body

cg27527887

−0.086760967

6.52E-05

0.05261645

10

/

/

cg11754974

0.081256084

9.46E-05

0.057515784

14

TRDJ3

TSS1500

cg16652347

0.084377724

2.97E-05

0.039173184

7

PLXNA4

Body

cg13828440

0.068921275

4.34E-06

0.021774546

12

KLRD1

TSS1500

cg18637238

0.061870615

2.68E-05

0.037570473

12

KLRK1

TSS1500

  1. BC breast cancer, NC normal controls, CHR chromosome, TSS1500 1500 bp of the start site of transcription.
  2. *The Δβ value (BC-NC) is the average β values of the BC group minus the average β values of the normal controls group. The differential methylated CpGs position were calculated by champ.DMP function. The adjusted p value were computed using the Benjamini–Hochberg method. Probe ID: identification of the probe (from 850 K BeadChip Array).
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