Fig. 3: Substrate scope of azomethine ylides 1.
From: Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides
Reaction conditions: 1 (0.26 mmol), 2a (0.20 mmol). Isolated yields were reported. Ee and dr were determined by chiral-stationary-phase HPLC analysis. a(S,SP)-tBu-FOXAP was used instead of (R)-DTBM-SEGPHOS in DCE (1.0 M). 18 h.
