Fig. 8: Examples of predicted inter-chain contact maps and contact-assisted docking.
From: Deep transfer learning for inter-chain contact predictions of transmembrane protein complexes
a–c The predicted inter-chain contact maps by DeepTMP, AlphaFold-Multimer (AFM), and ground-truth of native complexes for three example targets, 6UWM (a), 1UUN (b), and 5SVK (c). For reference, the native structures of three targets are also shown on the left. d, e The top predicted complex structures of our protein-protein docking program HSYMDOCK with (left panels) and without (right panels) using the predicted inter-chain contacts by DeepTMP on two targets, 4K7R (d) and 2JAF (e). The upper row is the top view and the lower row is the side view.
