Fig. 6: Hypoxia-induced seizure (SZ) state. | Nature Communications

Fig. 6: Hypoxia-induced seizure (SZ) state.

From: Mechanisms underlying pathological cortical bursts during metabolic depletion

Fig. 6

a Raster plot showing high firing rate activity in the SZ state at [K+]Buffer = 8 mM and [O2]Buffer = 11.33 mg/L, sorted by firing rate. b Average of the instantaneous firing rates (Φfr(t)). c Mean post-synaptic current Φsyn(t) of excitatory neurons. Blue line shows the average local extracellular oxygen concentration [O2]o. d Spectrogram showing wavelet-based time-frequency distribution of Φfr(t). e Excitation-inhibition (E-I) (im)balance shown for inputs to excitatory (black) and inhibitory (red) neurons.

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