Fig. 2: The free energy landscape corresponding to the mechanism shown in Fig. 1.
From: Thermodynamic principle to enhance enzymatic activity using the substrate affinity
The free energy changes (\(\Delta {G}_{1},\Delta {G}_{2}\)) and activation barriers (\({E}_{a1},{E}_{a1r},{E}_{a2}\))Â in the mathematical analysis are defined as indicated in the figure.
