Fig. 7: AVI strongly potentiates AZT and MEM in Bcc clinical isolates.

A Percent cumulative growth inhibition of 41 Bcc clinical isolates with or without AVI. The dashed line indicates the MIC₅₀, the concentration representing the MIC for 50% of the isolates. Data for panels A and B were summarized from Supplementary Data 2. B Resistance of Bcc clinical isolates to AZT, MEM, CAZ, and CFD with or without 8 µg mL⁻¹ AVI. CLSI resistance breakpoints for the Bcc: MEM ≥ 16 µg mL^-1; CAZ ≥ 32 µg mL⁻¹. CLSI resistance breakpoints for P. aeruginosa were used for AZT (≥32 µg mL⁻¹) and CFD (>4 µg mL⁻¹) as none exist for the Bcc. Source data are provided as a Source Data file.