Fig. 6: Zn²⁺-coordination structure of hZnT7.

Close-up views of the Zn²⁺-binding sites in the IF protomer in Zn²⁺ state 1 (a) and Zn²⁺ state 2 (b), in the OF protomer in Zn²⁺ state 3 (c), Zn²⁺ state 2 (d) and Zn²⁺ state 1 (e). The red spheres indicate bound Zn²⁺. The density map and Zn²⁺-binding residues are represented by blue mesh and yellow sticks, respectively. The main chains are represented by yellow ribbons. Red dashed lines indicate the distance between the Cα atoms of His70 and Asp244. Black dashed lines indicate the distances between the N_δ/N_ε atom of His70, His164 or His240 and Zn²⁺.