Fig. 1: Schematic overview on the cohort of NSCLC patients with acquired resistance to anti-PD-1 therapy. | Nature Communications

Fig. 1: Schematic overview on the cohort of NSCLC patients with acquired resistance to anti-PD-1 therapy.

From: Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype

Fig. 1

a Study scheme involved analysis of tumor biopsies collected before immunotherapy began and after the development of resistance. Whole exome sequencing, RNA sequencing, and imaging mass cytometry analyzes were performed on paraffin-embedded tumors. b FDG-PET-CT images of patient #4 before treatment with anti-PD1 (responding tumor), a response, and after development of resistance. c Swimmer’s plot illustrating the cohort of the patients included in the study and the length of anti-PD-1 treatment and development of resistance over the course of the disease.

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