Fig. 4: Scope of Benzamides with Substituents on the 7-Azaindole Ring.
From: Cobalt-catalyzed atroposelective C−H activation/annulation to access N−N axially chiral frameworks
Reaction conditions: 1 (0.2 mmol), 2a (0.24 mmol), Co(OAc)2·4H2O (0.02 mmol), L6 (0.04 mmol), AdCO2H (0.2 mmol) in 1,4-dioxane (2 mL) at 80 °C under O2 for 6 h, isolated yields. a20 mol% Co(OAc)2·4H2O, 10 h. ee enantiomeric excess.
